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Lymphoepithelial carcinoma of the salivary gland—A great cytologic mimicker in the head and neck region, and the first report of SSTR2 expression on cytologic material

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The patient is a 67-year-old Chinese female with no significant medical history, on follow-up for left facial swelling. Radiographic studies showed a deep-seated, lobulated hypoechoic mass in the left check… Click to show full abstract

The patient is a 67-year-old Chinese female with no significant medical history, on follow-up for left facial swelling. Radiographic studies showed a deep-seated, lobulated hypoechoic mass in the left check area (Figure 1A, B), slowly increasing in size from 2.1 1.9 1.1 cm to 3.3 2.6 1.4 cm over a two-year surveillance interval, worrisome for malignancy, likely a salivary gland tumour. The mass was intensely F-fluorodeoxyglucose (FDG)avid on positron emission tomography-computed tomography (PET-CT) (Figure 1C), raising the possibility of lymphomatous infiltrate. Fine-needle aspiration cytology (FNAC) was performed with rapid on-site evaluation (ROSE). Papanicolaou (Pap) and Diff-Quik (DQ)-stained smears were prepared, and an additional pass was obtained for cellblock. The smears and haematoxylin and eosin (H&E)-stained sections of the formalin-fixed paraffinembedded cell block showed a hyper cellular yield of intermediate to large

Keywords: carcinoma salivary; lymphoepithelial carcinoma; great cytologic; cytologic mimicker; salivary gland; gland great

Journal Title: Diagnostic Cytopathology
Year Published: 2022

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