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Carboxylated and undercarboxylated osteocalcin in metabolic complications of human obesity and prediabetes

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Carboxylated osteocalcin (Gla‐OC) participates in bone remodeling, whereas the undercarboxylated form (Glu‐OC) takes part in energy metabolism. This study was undertaken to compare the blood levels of Glu‐OC and Gla‐OC… Click to show full abstract

Carboxylated osteocalcin (Gla‐OC) participates in bone remodeling, whereas the undercarboxylated form (Glu‐OC) takes part in energy metabolism. This study was undertaken to compare the blood levels of Glu‐OC and Gla‐OC in nonobese, healthy obese, and prediabetic volunteers and correlate it with the metabolic markers of insulin resistance and early markers of inflammation.

Keywords: metabolic complications; complications human; osteocalcin metabolic; undercarboxylated osteocalcin; carboxylated undercarboxylated; human obesity

Journal Title: Diabetes/Metabolism Research and Reviews
Year Published: 2017

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