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T‐lymphocyte and glycemic status after vitamin D treatment in type 1 diabetes: A randomized controlled trial with sequential crossover

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Type 1 diabetes mellitus (T1D) is mediated by autoaggressive T effector cells with an underlying regulatory T‐cell (Treg) defect. Vitamin D deficiency is highly prevalent in T1D, which can aggravate… Click to show full abstract

Type 1 diabetes mellitus (T1D) is mediated by autoaggressive T effector cells with an underlying regulatory T‐cell (Treg) defect. Vitamin D deficiency is highly prevalent in T1D, which can aggravate immune dysfunction. High‐dose vitamin D treatment may enhance Tregs and improve metabolism in T1D patients.

Keywords: type diabetes; vitamin treatment; glycemic status; lymphocyte glycemic

Journal Title: Diabetes/Metabolism Research and Reviews
Year Published: 2017

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