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Diabetes is a complex progressive disease characterized by chronic hyperglycaemia and dyslipidaemia associated with endothelial dysfunction. Oxidized LDL (Ox‐LDL) is elevated in diabetes and may contribute to endothelial dysfunction. The… Click to show full abstract
Diabetes is a complex progressive disease characterized by chronic hyperglycaemia and dyslipidaemia associated with endothelial dysfunction. Oxidized LDL (Ox‐LDL) is elevated in diabetes and may contribute to endothelial dysfunction. The aim of this study was to relate the serum levels of Ox‐LDL with endothelial dysfunction in streptozotocin (STZ)‐diabetic rats and to further explore the changes in endothelial nitric oxide synthase (eNOS) and caveolin‐1 (CAV‐1) expression in primary aortic endothelial cells.
Journal Title: Diabetes/Metabolism Research and Reviews
Year Published: 2018
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