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Spatiotemporal control of gene expression boundaries using a feedforward loop

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A feedforward loop (FFL) is commonly observed in several biological networks. The FFL network motif has been mostly studied with respect to variation of the input signal in time, with… Click to show full abstract

A feedforward loop (FFL) is commonly observed in several biological networks. The FFL network motif has been mostly studied with respect to variation of the input signal in time, with only a few studies of FFL activity in a spatially distributed system such as morphogen‐mediated tissue patterning. However, most morphogen gradients also evolve in time.

Keywords: boundaries using; expression boundaries; gene expression; spatiotemporal control; control gene; feedforward loop

Journal Title: Developmental Dynamics
Year Published: 2020

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