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The DENND1A has been identified as a guanine nucleotide exchange factor for small GTPase Rab35, which functions in endocytic trafficking to mediate the recycling of selective cargos. Genetic alterations within… Click to show full abstract
The DENND1A has been identified as a guanine nucleotide exchange factor for small GTPase Rab35, which functions in endocytic trafficking to mediate the recycling of selective cargos. Genetic alterations within the DENND1A gene have been implicated in human disease such as polycystic ovary syndrome (PCOS). However, the role of DENND1A in developmental and reproductive processes is largely unknown.
Keywords:
dennd1a susceptibility;
ovary syndrome;
polycystic ovary;
susceptibility gene
Journal Title: Developmental Dynamics
Year Published: 2019
Link to full text (if available)
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Journal Title: Developmental Dynamics
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!