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The purpose of this review is to discuss the transforming growth factor beta (TGFB) binding proteins (LTBP) with respect to their participation in the activity of TGFB. We first describe… Click to show full abstract
The purpose of this review is to discuss the transforming growth factor beta (TGFB) binding proteins (LTBP) with respect to their participation in the activity of TGFB. We first describe pertinent aspects of the biology and cell function of the LTBPs. We then summarize the physiological consequences of LTBP loss in humans and mice. Finally, we consider a number of outstanding questions relating to LTBP function.
Keywords:
ltbps tgf;
tgf beta;
beta signaling;
role ltbps;
beta
Journal Title: Developmental Dynamics
Year Published: 2021
Link to full text (if available)
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Journal Title: Developmental Dynamics
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!