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The vitamin A derivative all‐trans retinoic acid (RA) regulates early stages of inner ear development. As the early disruption of the RA pathway results in profound mispatterning of the developing… Click to show full abstract
The vitamin A derivative all‐trans retinoic acid (RA) regulates early stages of inner ear development. As the early disruption of the RA pathway results in profound mispatterning of the developing inner ear, this confounds analyses of specific roles in later stages. Therefore, we used the temporal‐specific exposure of all‐trans RA or diethylaminobenzaldehyde to evaluate RA functions in late otic development.
Keywords:
signaling regulates;
inner ear;
acid signaling;
retinoic acid;
late stages;
regulates late
Journal Title: Developmental Dynamics
Year Published: 2022
Link to full text (if available)
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Journal Title: Developmental Dynamics
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!