"Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis"

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Frem1 has been linked to human face shape variation, dysmorphology, and malformation, but little is known about its regulation and biological role in facial development. Click to show full abstract

Frem1 has been linked to human face shape variation, dysmorphology, and malformation, but little is known about its regulation and biological role in facial development.

Keywords: hedgehog signaling; activity regulated; sonic hedgehog; frem1 activity; regulated sonic; signaling cranial

Journal Title: Developmental Dynamics
Year Published: 2022

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