Photo from wikipedia
Fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by progressive heterotopic ossification of muscle and connective tissues, is caused by autosomal dominant activating mutations in the type I receptor, ACVR1/ALK2.… Click to show full abstract
Fibrodysplasia ossificans progressiva (FOP), a rare disease characterized by progressive heterotopic ossification of muscle and connective tissues, is caused by autosomal dominant activating mutations in the type I receptor, ACVR1/ALK2. The classic human FOP variant, ACVR1R206H, shows increased bone morphogenetic protein (BMP) signaling and activation by activins.
Keywords:
comparison human;
zebrafish;
fop;
human acvr1;
acvr1 zebrafish;
functional comparison
Journal Title: Developmental Dynamics
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Developmental Dynamics
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!