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Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity

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Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular… Click to show full abstract

Gemcitabine is a commonly used antineoplastic agent used to treat a variety of cancers with rarely reported cardiac side effects. We describe a case of a 67‐year‐old woman with follicular lymphoma who experienced a rarely reported side effect of gemcitabine: cardiomyopathy. This case highlights a multiple hit mechanism of myocyte damage that may occur following the use of multiple cardio‐toxic agents despite their administration in doses not associated with cardiotoxicity.

Keywords: gemcitabine; case; multiple hit; cardiotoxicity; cardiomyopathy case

Journal Title: ESC Heart Failure
Year Published: 2017

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