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The effect of iron deficiency on cardiac resynchronization therapy: results from the RIDE‐CRT Study

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Cardiac resynchronization therapy (CRT) improves functional status, induces reverse left ventricular remodelling, and reduces hospitalization and mortality in patients with symptomatic heart failure, left ventricular systolic dysfunction, and QRS prolongation.… Click to show full abstract

Cardiac resynchronization therapy (CRT) improves functional status, induces reverse left ventricular remodelling, and reduces hospitalization and mortality in patients with symptomatic heart failure, left ventricular systolic dysfunction, and QRS prolongation. However, the impact of iron deficiency on CRT response remains largely unclear. The purpose of the study was to assess the effect of functional and absolute iron deficiency on reverse cardiac remodelling, clinical response, and outcome after CRT implantation.

Keywords: resynchronization therapy; iron; cardiac resynchronization; iron deficiency

Journal Title: ESC Heart Failure
Year Published: 2020

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