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The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure

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Measurement of B‐type natriuretic peptide (BNP) or N‐terminal pro‐BNP is recommended as part of the diagnostic workup of patients with suspected heart failure (HF). We evaluated the diagnostic and prognostic… Click to show full abstract

Measurement of B‐type natriuretic peptide (BNP) or N‐terminal pro‐BNP is recommended as part of the diagnostic workup of patients with suspected heart failure (HF). We evaluated the diagnostic and prognostic utility of the novel urinary proteomic classifier HF1, compared with BNP, in HF. HF1 consists of 85 unique urinary peptide fragments thought, mainly, to reflect collagen turnover.

Keywords: heart; diagnostic prognostic; prognostic utility; hf1; heart failure

Journal Title: ESC Heart Failure
Year Published: 2020

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