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Effect of β‐blocker on patients with moderate functional mitral regurgitation undergoing surgical aortic valve replacement

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The optimal treatment for severe aortic valve disease complicated with moderate function mitral regurgitation (FMR) remains controversial. Although isolated surgical aortic valve replacement (SAVR) is reasonable, previous studies also show… Click to show full abstract

The optimal treatment for severe aortic valve disease complicated with moderate function mitral regurgitation (FMR) remains controversial. Although isolated surgical aortic valve replacement (SAVR) is reasonable, previous studies also show that moderate FMR might deteriorate after surgical treatment and result in poorer prognosis. Because the left ventricular remodelling plays a critical role in the development of FMR, these patients might potentially benefit from the administration of β‐blocker (BB). Unfortunately, relevant clinical evidence is lacking. This study aimed to investigate the impact of post‐operative administration of BB on the outcomes of moderate FMR patients undergoing isolated SAVR.

Keywords: aortic valve; valve replacement; valve; surgical aortic; mitral regurgitation

Journal Title: ESC Heart Failure
Year Published: 2022

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