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Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study

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We aimed to explore the heterogeneous treatment effects (HTEs) for spironolactone treatment in patients with Heart failure with preserved ejection fraction (HFpEF) and examine the efficacy and safety of spironolactone… Click to show full abstract

We aimed to explore the heterogeneous treatment effects (HTEs) for spironolactone treatment in patients with Heart failure with preserved ejection fraction (HFpEF) and examine the efficacy and safety of spironolactone medication, ensuring a better individualized therapy.

Keywords: heart failure; preserved ejection; failure preserved; patients heart; heart

Journal Title: ESC Heart Failure
Year Published: 2022

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