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Clinical impacts of sacubitril/valsartan on patients eligible for cardiac resynchronization therapy

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Sacubitril/valsartan (SAC/VAL) has been used in patients with heart failure and reduced ejection fraction (HFrEF), and cardiac resynchronization therapy (CRT) could benefit the HFrEF patients with wide QRS durations. This… Click to show full abstract

Sacubitril/valsartan (SAC/VAL) has been used in patients with heart failure and reduced ejection fraction (HFrEF), and cardiac resynchronization therapy (CRT) could benefit the HFrEF patients with wide QRS durations. This study aimed to evaluate the clinical impacts of SAC/VAL on reverse cardiac remodelling in CRT‐eligible and CRT‐ineligible HFrEF patients with different QRS durations.

Keywords: cardiac resynchronization; sacubitril valsartan; resynchronization therapy; clinical impacts

Journal Title: ESC Heart Failure
Year Published: 2022

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