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Berberine up‐regulates miR‐340‐5p to protect myocardial ischaemia/reperfusion from HMGB1‐mediated inflammatory injury

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Myocardial ischaemia/reperfusion injury (MIRI) is a major cause of heart failure after myocardial infarction. Berberine (BBR) presents anti‐inflammatory and immunosuppressive properties in many diseases. Our research looked into the therapeutic… Click to show full abstract

Myocardial ischaemia/reperfusion injury (MIRI) is a major cause of heart failure after myocardial infarction. Berberine (BBR) presents anti‐inflammatory and immunosuppressive properties in many diseases. Our research looked into the therapeutic effects and mechanism of BBR in MIRI.

Keywords: ischaemia reperfusion; injury; myocardial ischaemia; berberine

Journal Title: ESC Heart Failure
Year Published: 2022

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