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Type 2 diabetes mellitus and cardiovascular health: Evidence of causal relationships in a European ancestry population

Type 2 diabetes mellitus (T2DM) is associated with increased cardiovascular disease (CVD) risk, but whether T2DM directly causes adverse cardiac remodelling is uncertain. We performed a comprehensive Mendelian randomization (MR)… Click to show full abstract

Type 2 diabetes mellitus (T2DM) is associated with increased cardiovascular disease (CVD) risk, but whether T2DM directly causes adverse cardiac remodelling is uncertain. We performed a comprehensive Mendelian randomization (MR) analysis to investigate the causal relevance of T2DM to CVD outcomes and cardiac structure/function.

Keywords: mellitus cardiovascular; diabetes mellitus; type diabetes; causal; cardiovascular health

Journal Title: ESC Heart Failure
Year Published: 2024

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