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Proteomic diversity of high‐density lipoprotein explains its association with clinical outcome in patients with heart failure

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Previously, low high‐density lipoprotein (HDL) cholesterol was found to be one of the strongest predictors of mortality and/or heart failure (HF) hospitalisation in patients with HF. We therefore performed in‐depth… Click to show full abstract

Previously, low high‐density lipoprotein (HDL) cholesterol was found to be one of the strongest predictors of mortality and/or heart failure (HF) hospitalisation in patients with HF. We therefore performed in‐depth investigation of the multifunctional HDL proteome to reveal underlying pathophysiological mechanisms explaining the association between HDL and clinical outcome.

Keywords: heart; high density; density lipoprotein; heart failure; clinical outcome

Journal Title: European Journal of Heart Failure
Year Published: 2018

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