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Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function

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Iron deficiency is common in patients with heart failure and associated with a poor cardiac function and higher mortality. How iron deficiency impairs cardiac function on a cellular level in… Click to show full abstract

Iron deficiency is common in patients with heart failure and associated with a poor cardiac function and higher mortality. How iron deficiency impairs cardiac function on a cellular level in the human setting is unknown. This study aims to determine the direct effects of iron deficiency and iron repletion on human cardiomyocytes.

Keywords: human cardiomyocytes; iron deficiency; function; iron; deficiency impairs

Journal Title: European Journal of Heart Failure
Year Published: 2018

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