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February 2019 at a glance: pathophysiology, exercise capacity, diuretics and valve disease

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Obesity may cause a distinct phenotype of heart failure (HF) with preserved ejection (HFpEF), characterized by plasma volume expansion, cardiac chamber overfilling and reduced ventricular compliance.1 Milton Packer has proposed… Click to show full abstract

Obesity may cause a distinct phenotype of heart failure (HF) with preserved ejection (HFpEF), characterized by plasma volume expansion, cardiac chamber overfilling and reduced ventricular compliance.1 Milton Packer has proposed a clinical classification of obese patients with HFpEF based on plasma volume status, left ventricular (LV) dimensions and natriuretic peptide levels.2 This classification may provide a framework for better targeted treatment of obese HFpEF patients.

Keywords: february 2019; 2019 glance; exercise capacity; pathophysiology exercise; capacity diuretics; glance pathophysiology

Journal Title: European Journal of Heart Failure
Year Published: 2019

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