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The clinical significance of interleukin‐6 in heart failure: results from the BIOSTAT‐CHF study

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Inflammation is a central process in the pathophysiology of heart failure (HF), but trials targeting tumour necrosis factor (TNF)‐α were largely unsuccessful. Interleukin (IL)‐6 is an important inflammatory mediator and… Click to show full abstract

Inflammation is a central process in the pathophysiology of heart failure (HF), but trials targeting tumour necrosis factor (TNF)‐α were largely unsuccessful. Interleukin (IL)‐6 is an important inflammatory mediator and might constitute a potential pharmacologic target in HF. However, little is known regarding the association between IL‐6 and clinical characteristics, outcomes and other inflammatory biomarkers in HF. We thus aimed to identify and characterize these associations.

Keywords: significance interleukin; interleukin heart; heart; heart failure; clinical significance

Journal Title: European Journal of Heart Failure
Year Published: 2019

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