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Functional mitral regurgitation and left atrial myopathy in heart failure with preserved ejection fraction

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Mild to moderate functional mitral regurgitation (MR) is common in patients with heart failure and preserved ejection fraction (HFpEF) where it is usually considered as an innocent bystander. We hypothesized… Click to show full abstract

Mild to moderate functional mitral regurgitation (MR) is common in patients with heart failure and preserved ejection fraction (HFpEF) where it is usually considered as an innocent bystander. We hypothesized that MR in HFpEF reflects greater left atrial (LA) myopathy, leading to more adverse haemodynamics and poorer exercise reserve.

Keywords: failure preserved; heart; functional mitral; mitral regurgitation; heart failure

Journal Title: European Journal of Heart Failure
Year Published: 2020

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