In general, guideline recommendations reflect, summarize and interpret the latest available evidence for assisting health care pro-fessionals in proposing the best treatment strategy for groups of patients. Changes in guidelines… Click to show full abstract
In general, guideline recommendations reflect, summarize and interpret the latest available evidence for assisting health care pro-fessionals in proposing the best treatment strategy for groups of patients. Changes in guidelines are usually based on new data from randomized clinical trials (RCTs) or large registry studies support-ing new recommendations or the up- or downgrading of existing recommendations with their respective level of evidence (LoE). The currently published 202 1 European Society of Cardiology (ESC)/European Association of Cardio-Thoracic Surgery (EACTS) guidelines for the management of valvular heart disease introduced several
               
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