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Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock

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Cardiogenic shock (CS) with variable systemic inflammation may be responsible for patient heterogeneity and the exceedingly high mortality rate. Cardiovascular events have been associated with clonal haematopoiesis (CH) where specific… Click to show full abstract

Cardiogenic shock (CS) with variable systemic inflammation may be responsible for patient heterogeneity and the exceedingly high mortality rate. Cardiovascular events have been associated with clonal haematopoiesis (CH) where specific gene mutations in haematopoietic stem cells lead to clonal expansion and the development of inflammation. This study aims to assess the prevalence of CH and its association with survival in a population of CS patients in a quaternary centre.

Keywords: clonal haematopoiesis; mortality; haematopoiesis associated; cardiogenic shock

Journal Title: European Journal of Heart Failure
Year Published: 2022

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