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Renal effects of empagliflozin in patients hospitalized for acute heart failure: from the EMPULSE trial

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The sodium–glucose cotransporter 2 (SGLT2) inhibitor empagliflozin improved clinical outcomes in patients hospitalized for acute heart failure. In patients with chronic heart failure, SGLT2 inhibitors cause an early decline in… Click to show full abstract

The sodium–glucose cotransporter 2 (SGLT2) inhibitor empagliflozin improved clinical outcomes in patients hospitalized for acute heart failure. In patients with chronic heart failure, SGLT2 inhibitors cause an early decline in estimated glomerular filtration rate (eGFR) followed by a slower eGFR decline over time than placebo. However, the effects of SGLT2 inhibitors on renal function during a hospital admission for acute heart failure remain largely unknown.

Keywords: patients hospitalized; heart failure; acute heart; heart; hospitalized acute

Journal Title: European Journal of Heart Failure
Year Published: 2022

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