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Serially measured circulating microRNAs and adverse clinical outcomes in patients with acute heart failure

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Previous studies have identified candidate circulating microRNAs (circmiRs) as biomarkers for heart failure (HF) using relatively insensitive arrays, validated in small cohorts. The present study used RNA sequencing to identify… Click to show full abstract

Previous studies have identified candidate circulating microRNAs (circmiRs) as biomarkers for heart failure (HF) using relatively insensitive arrays, validated in small cohorts. The present study used RNA sequencing to identify novel candidate circmiRs and compared these with previously identified circmiRs in a large, prospective cohort of patients with acute HF (AHF).

Keywords: heart; patients acute; failure serially; heart failure; circulating micrornas

Journal Title: European Journal of Heart Failure
Year Published: 2018

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