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We have analyzed T cell receptor repertoires in a unique set of thymus samples from a pair of monozygotic twins. While genetics affect the V(D)J rearrangement and generation of junctional… Click to show full abstract
We have analyzed T cell receptor repertoires in a unique set of thymus samples from a pair of monozygotic twins. While genetics affect the V(D)J rearrangement and generation of junctional sequences, the thymic selections seem largely stochastic and import no detectable inheritable effect at clonal level.
Keywords:
component human;
inheritable component;
identifying inheritable;
generation;
cell;
human thymic
Journal Title: European Journal of Immunology
Year Published: 2019
Link to full text (if available)
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Journal Title: European Journal of Immunology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!