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IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome

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Analysis of serum cytokine levels in Wiskott–Aldrich syndrome patients pre‐ and post‐ treatment reveals IL‐18 as a stable and reliable marker of inflammation. Definitive stem cell treatment with good myeloid… Click to show full abstract

Analysis of serum cytokine levels in Wiskott–Aldrich syndrome patients pre‐ and post‐ treatment reveals IL‐18 as a stable and reliable marker of inflammation. Definitive stem cell treatment with good myeloid correction correlates with resolution of inflammation and reduction of circulating IL‐18, highlighting the importance of actin cytoskeletal regulation of myeloid cells in control of inflammation.

Keywords: potential inflammation; inflammation biomarker; biomarker wiskott; inflammation; aldrich syndrome; wiskott aldrich

Journal Title: European Journal of Immunology
Year Published: 2021

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