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Platelets regulate human inflammatory responses that lead to disease. However, the role of platelets in tuberculosis (TB) pathogenesis is still unclear. Here, we show that patients with active TB have… Click to show full abstract
Platelets regulate human inflammatory responses that lead to disease. However, the role of platelets in tuberculosis (TB) pathogenesis is still unclear. Here, we show that patients with active TB have a high number of platelets in peripheral blood and a low number of lymphocytes leading to a high platelets to lymphocytes ratio (PL ratio). Moreover, the serum concentration of different mediators promoting platelet differentiation or associated with platelet activation is increased in active TB.
Keywords:
tuberculosis patients;
tuberculosis;
lung lesions;
accumulate lung;
platelets accumulate;
lesions tuberculosis
Journal Title: European Journal of Immunology
Year Published: 2022
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Journal Title: European Journal of Immunology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!