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Human dendritic cells (DC) have been divided into several subsets based on their phenotype and ontogeny. Recent high throughput single-cell methods have revealed additional heterogeneity within human DC subsets, and… Click to show full abstract
Human dendritic cells (DC) have been divided into several subsets based on their phenotype and ontogeny. Recent high throughput single-cell methods have revealed additional heterogeneity within human DC subsets, and new subpopulations have been proposed. In this review, we provide an updated view of the human DC subsets and of their ontogeny supported by recent clinical studies . We also summarize their main characteristics, including their functional specialization. This article is protected by copyright. All rights reserved.
Journal Title: European journal of immunology
Year Published: 2022
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