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Cytokine‐induced transient monocyte IL‐7Ra expression and the serum milieu in tuberculosis

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Bacterial components and cytokines induce IL‐7 receptor (IL‐7Rα) expression in monocytes. Aberrant low IL‐7Rα expression of monocytes has been identified as a feature of tuberculosis immunopathology. Here, we investigated the… Click to show full abstract

Bacterial components and cytokines induce IL‐7 receptor (IL‐7Rα) expression in monocytes. Aberrant low IL‐7Rα expression of monocytes has been identified as a feature of tuberculosis immunopathology. Here, we investigated the mechanisms underlying IL‐7Rα regulation of monocytes and tuberculosis serum effects on IL‐7Rα expression.

Keywords: tuberculosis; cytokine induced; induced transient; expression; monocyte 7ra; transient monocyte

Journal Title: European Journal of Immunology
Year Published: 2022

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