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This review summarizes the intermolecular PdII-catalyzed dehydrogenation procedures leading to regioselective coupling of alcohols with (hetero)arenes bearing tethered coordinating groups. Unusual oxidative conditions of catalyst regeneration are required, and the… Click to show full abstract
This review summarizes the intermolecular PdII-catalyzed dehydrogenation procedures leading to regioselective coupling of alcohols with (hetero)arenes bearing tethered coordinating groups. Unusual oxidative conditions of catalyst regeneration are required, and the optimum oxidant varies with the substrate. Emphasis is placed on the mechanism of these intriguing reactions. Either PdII–Pd0 or PdII–PdIV redox catalytic cycles, possibly with PdIII intermediates, could be involved, depending on the directing group.
Journal Title: European Journal of Organic Chemistry
Year Published: 2017
Link to full text (if available)
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