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Herein, we describe a metal-free, iodosobenzenediacetate mediated trans-aziridination of zerumbone by the direct use of sulphonamides. The preliminary in vitro-screening showed better anti-proliferative and anti-diabetic activity compared to parent compound… Click to show full abstract
Herein, we describe a metal-free, iodosobenzenediacetate mediated trans-aziridination of zerumbone by the direct use of sulphonamides. The preliminary in vitro-screening showed better anti-proliferative and anti-diabetic activity compared to parent compound zerumbone.
Keywords:
free trans;
aziridination zerumbone;
trans aziridination;
metal free;
synthesis biological;
zerumbone synthesis
Journal Title: European Journal of Organic Chemistry
Year Published: 2017
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Journal Title: European Journal of Organic Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!