A wide range of substituted pyridine derivatives were synthesized in moderate to good yields from a N-propargylic α-enamino ester. The synthetic strategy involves regioselective addition of propargyl amine to the… Click to show full abstract
A wide range of substituted pyridine derivatives were synthesized in moderate to good yields from a N-propargylic α-enamino ester. The synthetic strategy involves regioselective addition of propargyl amine to the α-carbon of the alkynyl ester to produce N-propargylic α-enamino ester which acts as the key intermediate for the synthesis of the pyridine derivatives.
Keywords:
substituted pyridine;
synthesis;
propargylic enamino;
pyridine derivatives
Journal Title: European Journal of Organic Chemistry
Year Published: 2017
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Journal Title: European Journal of Organic Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!