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Iron Nitrate-Catalyzed Oxidative Esterification of Aldehydes and Alcohols with NHPI: Efficient Synthesis of N-hydroxyimide Esters

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An Fe(NO3)3*9H2O-catalyzed cross-dehydrogenative coupling reaction between N-hydroxyphthalimide (NHPI) or N-hydroxysuccinimide (NHSI) and aldehydes or alcohols in the air has been described. This transformation provided an efficient approach to prepare N-hydroxyimide… Click to show full abstract

An Fe(NO3)3*9H2O-catalyzed cross-dehydrogenative coupling reaction between N-hydroxyphthalimide (NHPI) or N-hydroxysuccinimide (NHSI) and aldehydes or alcohols in the air has been described. This transformation provided an efficient approach to prepare N-hydroxyimide ester derivatives with wide substrate scope in moderate to excellent yields.

Keywords: iron nitrate; esterification aldehydes; nitrate catalyzed; aldehydes alcohols; oxidative esterification; catalyzed oxidative

Journal Title: European Journal of Organic Chemistry
Year Published: 2017

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