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Metal‐free iodine‐mediated deoxygenation of alcohols in the position α to electron‐withdrawing groups

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The use of a substoichiometric amount of molecular iodine in the presence of PPh3 and pyridine effects a direct deoxygenation of primary and secondary alcohols in positions α to a… Click to show full abstract

The use of a substoichiometric amount of molecular iodine in the presence of PPh3 and pyridine effects a direct deoxygenation of primary and secondary alcohols in positions α to a variety of activating electron‐withdrawing groups, including ketones, esters, amides, imides and nitrile groups.

Keywords: electron withdrawing; withdrawing groups; metal free; free iodine; deoxygenation

Journal Title: European Journal of Organic Chemistry
Year Published: 2018

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