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In this work, the synthesis of oxazolo[4,5-d]pyrimidines and oxazolo[5,4-d]pyrimidines is reviewed. The review is focused on the construction of the scaffold rather than on its further modification. Nevertheless, selected examples… Click to show full abstract
In this work, the synthesis of oxazolo[4,5-d]pyrimidines and oxazolo[5,4-d]pyrimidines is reviewed. The review is focused on the construction of the scaffold rather than on its further modification. Nevertheless, selected examples illustrate some of the most common modifications of these scaffolds. The synthetic part is complemented by an overview of their biological activity. This review covers literature and patents from 1967 until the present.
Keywords:
biological activity;
activity oxazolopyrimidines;
chemistry;
synthesis biological;
activity
Journal Title: European Journal of Organic Chemistry
Year Published: 2018
Link to full text (if available)
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Journal Title: European Journal of Organic Chemistry
Year Published: 2018
Link to full text (if available)
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recommendations!