A new strategy for the synthesis of 3‐substituted phthalides has been developed via a Lewis acid‐catalyzed intramolecular ring opening of aziridines with esters. Broad substrate scope, good yields and mild… Click to show full abstract
A new strategy for the synthesis of 3‐substituted phthalides has been developed via a Lewis acid‐catalyzed intramolecular ring opening of aziridines with esters. Broad substrate scope, good yields and mild conditions made the cyclization reaction very suitable for the rapid construction of libraries of 3‐substituted phthalide compounds.
Keywords:
catalyzed intramolecular;
lewis acid;
substituted phthalides;
via lewis;
acid catalyzed;
intramolecular ring
Journal Title: European Journal of Organic Chemistry
Year Published: 2024
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Journal Title: European Journal of Organic Chemistry
Year Published: 2024
Link to full text (if available)
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recommendations!