An additive‐free and diastereoselective [4 + 1] annulation between ortho‐hydroxyphenyl‐substituted para‐quinone methides and CF3‐substituted imidoyl sulfoxonium ylides is developed, providing a facile and practical route to diverse trans‐2,3‐dihydrobenzofurans with high… Click to show full abstract
An additive‐free and diastereoselective [4 + 1] annulation between ortho‐hydroxyphenyl‐substituted para‐quinone methides and CF3‐substituted imidoyl sulfoxonium ylides is developed, providing a facile and practical route to diverse trans‐2,3‐dihydrobenzofurans with high efficiency. This protocol features mild conditions, broad substrate scope and easy to operate.
Keywords:
annulation;
diastereoselective synthesis;
synthesis trans;
trans disubstituted;
additive free;
free diastereoselective
Journal Title: European Journal of Organic Chemistry
Year Published: 2024
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Journal Title: European Journal of Organic Chemistry
Year Published: 2024
Link to full text (if available)
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recommendations!