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Delta‐9‐tetrahydrocannabinol decreases masticatory muscle sensitization in female rats through peripheral cannabinoid receptor activation

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This study investigated whether intramuscular injection of delta‐9‐tetrahydrocannabinol (THC), by acting on peripheral cannabinoid (CB) receptors, could decrease nerve growth factor (NGF)‐induced sensitization in female rat masseter muscle; a model… Click to show full abstract

This study investigated whether intramuscular injection of delta‐9‐tetrahydrocannabinol (THC), by acting on peripheral cannabinoid (CB) receptors, could decrease nerve growth factor (NGF)‐induced sensitization in female rat masseter muscle; a model which mimics the symptoms of myofascial temporomandibular disorders.

Keywords: peripheral cannabinoid; muscle; sensitization female; delta tetrahydrocannabinol

Journal Title: European Journal of Pain
Year Published: 2017

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