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Evidence for the modulation of nociception in mice by central mast cells

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Hyperalgesia that develops following nerve ligation corresponds temporally and in magnitude with the number of thalamic mast cells located contralateral to the ligature. We tested the possibility that mast cells… Click to show full abstract

Hyperalgesia that develops following nerve ligation corresponds temporally and in magnitude with the number of thalamic mast cells located contralateral to the ligature. We tested the possibility that mast cells modulate nociception centrally, similar to their role in the periphery.

Keywords: evidence modulation; nociception mice; mast cells; mast; modulation nociception

Journal Title: European Journal of Pain
Year Published: 2017

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