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Dopamine (DA) is thought to be important to local hippocampal networks integrity during spatial working memory (sWM) processing. Chronic pain may contribute to deficient dopaminergic signalling, which may in turn… Click to show full abstract
Dopamine (DA) is thought to be important to local hippocampal networks integrity during spatial working memory (sWM) processing. Chronic pain may contribute to deficient dopaminergic signalling, which may in turn affect cognition. However, the neural mechanisms that determine this impairment are poorly understood. Here, we evaluated whether the sWM impairment characteristic of animal models of chronic pain is dependent on DA D2 receptor (D2r) activity.
Keywords:
blockade dopamine;
receptors disrupts;
dopamine receptors;
working memory;
pain
Journal Title: European Journal of Pain
Year Published: 2018
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Journal Title: European Journal of Pain
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!