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A combination of analgesic agents with different mechanisms can induce additive or synergistic analgesia. The N‐type voltage‐dependent calcium channel (N‐VDCC) is a novel therapeutic target for pain control. In addition… Click to show full abstract
A combination of analgesic agents with different mechanisms can induce additive or synergistic analgesia. The N‐type voltage‐dependent calcium channel (N‐VDCC) is a novel therapeutic target for pain control. In addition to providing effective pain relief when used alone, N‐VDCC blockers produce synergistic analgesia when used in combination with opiates. However, the interaction between N‐VDCC blockers and nonsteroidal anti‐inflammatory drugs (NSAIDs) remains unclear.
Keywords:
type voltage;
calcium channel;
dependent calcium;
voltage dependent;
pain
Journal Title: European Journal of Pain
Year Published: 2019
Link to full text (if available)
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Journal Title: European Journal of Pain
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!