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The effect of experimental pain on the excitability of the corticospinal tract in humans: A systematic review and meta‐analysis

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Pain influences motor control. Previous reviews observed that pain reduces the excitability of corticospinal projections to muscles tested with transcranial magnetic stimulation. However, the independent effect of the type of… Click to show full abstract

Pain influences motor control. Previous reviews observed that pain reduces the excitability of corticospinal projections to muscles tested with transcranial magnetic stimulation. However, the independent effect of the type of pain models (tonic, phasic), pain location and tissues targeted (e.g. muscle, skin) remains unexplored. The objective of this review was to determine the influence of experimental pain and of different methodological factors on the corticospinal excitability.

Keywords: review; experimental pain; excitability corticospinal; effect experimental; pain

Journal Title: European Journal of Pain
Year Published: 2021

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