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Mu and delta opioid receptor knockout mice show increased colonic sensitivity

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Opiates act through opioid receptors to diminish pain. Here, we investigated whether mu (MOR) and delta (DOR) receptor endogenous activity assessed in the whole mouse body or in particular at… Click to show full abstract

Opiates act through opioid receptors to diminish pain. Here, we investigated whether mu (MOR) and delta (DOR) receptor endogenous activity assessed in the whole mouse body or in particular at peripheral receptors on primary nociceptive neurons, control colonic pain.

Keywords: opioid receptor; knockout mice; delta opioid; receptor; mice show; receptor knockout

Journal Title: European Journal of Pain
Year Published: 2017

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