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A Two-step Strategy for the Selective and Sensitive Detection of Dopamine with Glassy Carbon Electrodes

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A new strategy is developed for using cyclic voltammetry technique to achieve sensitive and selective detection of dopamine on glassy carbon electrodes. The proposed method involves two steps, in which… Click to show full abstract

A new strategy is developed for using cyclic voltammetry technique to achieve sensitive and selective detection of dopamine on glassy carbon electrodes. The proposed method involves two steps, in which the cyclic voltammetric measurement is preceded by a brief period of potentiostatic treatment of the analyte solution. With this two-step strategy redox peaks could be seen at dopamine concentration as low as 5 μM. In the co-presence of ascorbic acid and uric acid, there are three well-resolved anodic peaks with the peak separation between ascorbic acid and dopamine larger than 230 mV. The fact that no pre-modification of the glassy carbon electrode is needed and the glassy carbon electrodes can be readily recovered after each measurement makes this new method attractive for the sensitive detection of dopamine.

Keywords: glassy carbon; carbon; carbon electrodes; detection dopamine; strategy

Journal Title: Electroanalysis
Year Published: 2017

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