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The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study

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We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin‐dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)]… Click to show full abstract

We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin‐dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA)] and temporal lobe epilepsy (TLE), using bioinformatics tools. We hypothesized that there are shared genetic variations among these four conditions.

Keywords: temporal lobe; autoimmune disorders; systemic autoimmune; lobe epilepsy

Journal Title: Epilepsia Open
Year Published: 2023

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