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Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam

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We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores),… Click to show full abstract

We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores), considering the effect of levetiracetam, which is commonly given after severe TBI.

Keywords: plasma protein; protein biomarkers; brain; early preclinical; plasma; preclinical plasma

Journal Title: Epilepsia Open
Year Published: 2023

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