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Chromosomal aberrations are known to drive metastatic spread, but their profile is still elusive in carcinoma of unknown primary (CUP). Therefore, the aim of this study was to characterize the… Click to show full abstract
Chromosomal aberrations are known to drive metastatic spread, but their profile is still elusive in carcinoma of unknown primary (CUP). Therefore, the aim of this study was to characterize the chromosomal aberration pattern in CUP depending on histological and clinical features and to assess its prognostic impact together with chromothripsis, tumor mutational burden (TMB), microsatellite instability (MSI), and mutational profiles as potential prognostic biomarkers.
Keywords:
prognostic impact;
unknown primary;
tumor mutational;
mutational burden;
carcinoma unknown
Journal Title: Genes
Year Published: 2022
Link to full text (if available)
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Journal Title: Genes
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!